Postdoc / PhD (all genders) for Computational Immunology

At the Hamburg Center for Translational Immunology (HCTI) within the University Medical Center Hamburg-Eppendorf (UKE), we are actively seeking highly motivated Ph.D. and postdoctoral fellows with a robust background in computational immunology for positions in the laboratory of Nicola Gagliani.

Our research focus centers on investigating the fundamental molecular and cellular mechanisms of T cell biology. Specifically, we explore how T cells adapt to environmental changes and ultimately contribute to either mediating physiological responses to pathogens or engaging in pathological tissue-damaging processes (Vesely et al., Cell (2019), Zhao Yu et al., Science Immunology (2021), Tintelnot J. et al., Nature (2023), Siracusa F. et al., Nature Immunology (2023), and Siracusa F. et al., Trends in Immunology (2023)).

In the upcoming years, we are dedicated to use systems immunology to decode the intricate interplay between environmental triggers and the immune system, with a specific emphasis on T cells resident in the different organs. Our research aims to elucidate how these organ-resident T cells adapt to various tissues and consequently influence the development of both physiological and pathological immune responses, including tumor development. A key aspect of this project is to use and develop new compuatational tools to transform big data into knlowdge.

The laboratory of Nicola Gagliani is funded by DFG and ERC grants, providing a unique opportunity for fellows to access a combination of state-of-the-art techniques and multiomics data to answer key biological questions.

We can also offer:

• International and multidisciplinary environment at the University Medical Center Hamburg-Eppendorf, a leading institution in Europe (Germany).
• Possibility to collaborate and being co-supervised with Prof. Jan Baumbach, Computational Systems Biology Lab, (UHH, Hamburg) to further improve the computational expertise.
• Access to the institution's soft skills program, including training in presenting skills and scientific writing, as well as career-oriented courses.
• Mentoring focused on building the best possible career within and outside academia.
• Weekly scientific exchange through lab meetings and journal clubs.
• Opportunity to collaborate with research groups at the University of Yale (USA) and the Karolinska Institute (Sweden).

This position is temporary for 3 years due to project-related reasons.

• completed academic studies in bioinformatics, computational science, biology or similar, and if applicable a PhD or MD, or an equivalent degree
• expertise and commitment to computational biology
• experience in analyzing high-throughput sequencing data, single-cell or spatial data sets, in statistical data analysis, integration, and visualization, along with fluency in at least one data science language (R, Python, Matlab), is required for postdoc candidates and strongly recomanded Ph.D. candidates

• Regular pay according to TVöD/VKA; attractive company pension plan and various employee discounts
• 30 days of vacation; possibility of special leave
• Central location: Our clinic is centrally located at the beautiful Eppendorfer Park
• Sustainable travel: subsidies for the "Deutschlandticket" and Dr. Bike bicycle service
• Crisis-proof workplace, meaningful activity, appreciative interaction and open exchange of knowledge within the team; structured induction training
• Opportunity to actively shape and develop the working environment within the framework of our employee program (UKE INside).
• Family-friendly working environment: cooperation on childcare, free vacation care, advice for employees with relatives in need of care
• Excellent health, prevention and sports offers
• Healthy and varied lunch break: In addition to our canteen, there is a rich selection of culinary offerings just a few steps away, for example the "Health Kitchen" cafés and bistros, as well as other snack bars, bakers, a supermarket, etc.

We live diversity and value variety

We offer a work environment providing equal opportunities regardless of age, gender, sexual identity, disability, origin or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under-representation of one gender in the advertised area. Persons with severe disability with equal aptitude, competence and professional performance will be given priority. 

> Learn more about "Diversity at UKE" here.